Diffuse Large B-Cell Lymphoma of the Lacrimal Sac in a Japanese Patient
- PMID: 30687073
- PMCID: PMC6341361
- DOI: 10.1159/000495745
Diffuse Large B-Cell Lymphoma of the Lacrimal Sac in a Japanese Patient
Abstract
Purpose: To report a Japanese patient with diffuse large B-cell lymphoma (DLBCL) in the lacrimal sac.
Methods: This is a case report of a 52-year-old Japanese woman who presented with a 3-month history of epiphora on the right side and a 1-month history of swelling on the right medial canthal area. Lacrimal sac irrigation showed patency of the lacrimal drainage system. Imaging studies revealed a lacrimal sac mass with involvement of the nasolacrimal duct.
Results: Histopathology and immunohistochemistry of the biopsy specimen revealed DLBCL. Systemic workup revealed no other lesion. The patient received 6 cycles of R-CHOP regimen. After completion of the 5th cycle of R-CHOP, all of the symptoms had resolved.
Conclusion: We report a case of DLBCL in the lacrimal sac, which is the most common type of lacrimal sac lymphoma in Japan. Since DLBCL is one of the aggressive types of lymphoma, Japanese patients with lacrimal sac lymphoma tend to have a poor prognosis.
Keywords: Diffuse large B-cell lymphoma; Japanese patients; Lacrimal sac.
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References
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