Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Dec;10(Suppl 34):S4262-S4279.
doi: 10.21037/jtd.2018.11.48.

Cardiovascular outcomes of continuous positive airway pressure therapy for obstructive sleep apnea

Yüksel Peker  1   2   3   4 , Baran Balcan  5
Affiliations
Review

Cardiovascular outcomes of continuous positive airway pressure therapy for obstructive sleep apnea

Yüksel Peker et al. J Thorac Dis. 2018 Dec.

Abstract

Obstructive sleep apnea is a common disorder with increased risk for cardiovascular morbidity and mortality. The first choice of treatment of obstructive sleep apnea is continuous positive airway pressure, which reduces excessive daytime sleepiness and improves quality of life in sleep clinic cohorts. Nevertheless, the majority of patients with cardiovascular disease and concomitant obstructive sleep apnea do not report daytime sleepiness, and adherence to treatment is insufficient particularly in this group. The current article aims to give an updated overview of the impact of continuous positive airway pressure therapy on cardiovascular outcomes mainly based on the observational studies and the recent randomized controlled trials.

Keywords: Obstructive sleep apnea (OSA); cardiovascular outcomes; continuous positive airway pressure (CPAP); randomized controlled trial (RCT).

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: Dr. Y Peker reports grants from ResMed, during the conduct of the RICCADSA study mentioned in the current review; personal fees from BresoTec Inc., and personal fees from Philips-Respironics, outside the submitted work. Dr. B Balcan has no conflicts of interest to declare.

References

    1. Heinzer R, Vat S, Marques-Vidal P, et al. Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study. Lancet Respir Med 2015;3:310-8. 10.1016/S2213-2600(15)00043-0 - DOI - PMC - PubMed
    1. Berry RB, Budhiraja R, Gottlieb DJ, et al. Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 2012;8:597-619. - PMC - PubMed
    1. Javaheri S, Barbe F, Campos-Rodriguez F, et al. Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences. J Am Coll Cardiol 2017;69:841-58. 10.1016/j.jacc.2016.11.069 - DOI - PMC - PubMed
    1. Khayat R, Pleister A. Consequences of Obstructive Sleep Apnea: Cardiovascular Risk of Obstructive Sleep Apnea and Whether Continuous Positive Airway Pressure Reduces that Risk. Sleep Med Clin 2016;11:273-86. 10.1016/j.jsmc.2016.05.002 - DOI - PubMed
    1. Dedhia RC, Strollo PJ, Soose RJ. Upper Airway Stimulation for Obstructive Sleep Apnea: Past, Present, and Future. Sleep 2015;38:899-906. - PMC - PubMed