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Clinical Trial
. 2019 May 2;68(10):1750-1753.
doi: 10.1093/cid/ciy897.

Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus-infected Children With Suspected Tuberculosis

Laurence Borand  1 , Agathe de Lauzanne  1 , Ngoc Lan Nguyen  2 , Sokleaph Cheng  3 , Thu Hang Pham  4 , Sara Eyangoh  5 , Abdoul-Salam Ouedraogo  6 , Vibol Ung  7   8 , Philippe Msellati  9 , Mathurin Tejiokem  10 , Boubacar Nacro  11 , Malin Inghammar  1   12 , Bunnet Dim  1 , Christophe Delacourt  13 , Sylvain Godreuil  14   15 , Stéphane Blanche  16 , Olivier Marcy  1   17 ; Pediatric Asian African Network for Tuberculosis and HIV Research (PAANTHER) Study Group
Affiliations
Clinical Trial

Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus-infected Children With Suspected Tuberculosis

Laurence Borand et al. Clin Infect Dis. .

Abstract

We enrolled 427 human immunodeficiency virus-infected children (median age, 7.3 years), 59.2% severely immunodeficient, with suspected tuberculosis in Southeast Asian and African settings. Nontuberculous mycobacteria were isolated in 46 children (10.8%); 45.7% of isolates were Mycobacterium avium complex. Southeast Asian origin, age 5-9 years, and severe immunodeficiency were independently associated with nontuberculous mycobacteria isolation.

Clinical trials registration: NCT01331811.

Keywords: HIV; children; nontuberculous mycobacteria; tuberculosis.

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References

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