Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Mar 22;58(13):4264-4270.
doi: 10.1002/anie.201814172. Epub 2019 Feb 27.

Total Synthesis of Actinorhodin

Mamiko Ninomiya  1 , Yoshio Ando  1 , Fumitaka Kudo  1 , Ken Ohmori  1 , Keisuke Suzuki  1
Affiliations

Total Synthesis of Actinorhodin

Mamiko Ninomiya et al. Angew Chem Int Ed Engl. .

Abstract

The enantioselective total synthesis of actinorhodin (1) is described. The synthesis features 1) dual benzyne reactions en route to the monomer, 2) the trans-selective installation of the side chain, and 3) a regioselective oxidative dimerization.

Keywords: dimerization; natural products; pigments; pyranonaphthoquinones; total synthesis.

PubMed Disclaimer

Publication types

LinkOut - more resources