Cellular collaboration in the production of human leucocyte migration inhibition factor
- PMID: 306961
- PMCID: PMC1457206
Cellular collaboration in the production of human leucocyte migration inhibition factor
Abstract
The participation of cell subpopulations in the expression of leucocyte migration inhibition factor (LMIF) in response to Concanavalin A and Protein A was evaluated for cells isolated from the peripheral blood of five healthy subjects. LMIF activity could not be attributed to the function of T cells, B enriched cells, or monocytes acting alone, or to a combination of B enriched cells and monocytes. The LMIF response was the result of a collaborative event that occurred between T cells and B enriched cells, or between T cells and monocytes.
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