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Case Reports
. 2018 Nov-Dec;23(6):486-489.
doi: 10.5863/1551-6776-23.6.486.

Dexmedetomidine-Associated Fever in a Critically Ill Obese Child

R Zachary Thompson, Lori McDonald, Keegan Ziemba, Joseph D Tobias, Claire A Stewart
Case Reports

Dexmedetomidine-Associated Fever in a Critically Ill Obese Child

R Zachary Thompson et al. J Pediatr Pharmacol Ther. 2018 Nov-Dec.

Abstract

Dexmedetomidine use in the pediatric intensive care unit has increased in recent years. Reports of dexmedetomidine-associated drug fever have been described in adult patients; however, this has not been reported in the pediatric population. We report a case of persistent fever that resolved with the discontinuation of dexmedetomidine and successful transition to clonidine. This is the first report of dexmedetomidine drug fever in a pediatric patient.

Keywords: adverse drug effect; critical care; dexmedetomidine; drug fever; pediatric.

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Conflict of interest statement

Disclosure The authors declare no conflicts or financial interest in any product or service mentioned in the manuscript, including grants, equipment, medications, employment, gifts, and honoraria. The authors had full access to all patient information in this report and take responsibility for the integrity and accuracy of the report.

Figures

Figure.
Figure.
Temperature curve and dexmedetomidine infusion dose.
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