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Review
. 2018 Nov 22;90(10):109-114.
doi: 10.26442/terarkh20189010109-114.

From Schönlein-Henoch purpura to IgA-vasculitis: pathogenetic aspects of the disease

S V Guliaev  1 , L A Strizhakov  1 , S V Moiseev  1 , V V Fomin  1
Affiliations
Review

From Schönlein-Henoch purpura to IgA-vasculitis: pathogenetic aspects of the disease

S V Guliaev et al. Ter Arkh. .

Abstract

Investigation's history and nomenclature's evolution of the IgA-vasculitis are presented in the article. Pathogenesis of the renal and skin damages is discussed in details, particularly abnormalities of the IgA-immunity and systemic endotoxemia. Relevant world's literature is cited.

Keywords: IgA-nephropathy; IgA-vasculitis; Schönlein–Henoch purpura; Shwartzman reaction; defective IgA glycosylation; endotoxemia; hemorrhagic vasculitis; systemic vasculitides.

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