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Review
. 2018 Apr 19;90(4):100-104.
doi: 10.26442/terarkh2018904100-104.

The role of the mLDL-induced activation of the complement system classical pathway and C3 expression stimulation in atherosclerosis

O M Drapkina  1 , B B Gegenava  1 , V V Fomin  1
Affiliations
Review

The role of the mLDL-induced activation of the complement system classical pathway and C3 expression stimulation in atherosclerosis

O M Drapkina et al. Ter Arkh. .

Abstract

The role of modified low density lipoprotein in the activation of the classical pathway of the complement system and increasing expression C3 gene in human macrophages is described, role of these processes on the progression of atherosclerotic vascular lesions is considering.

Keywords: complement; modified LDL; the C3 gene expression; the classical pathway.

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