Amyloidosis of the Brain and Heart: Two Sides of the Same Coin?

Affiliations

¹ Department of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
² Clinical Cardiovascular Research Laboratory for the Elderly, Columbia University Irving Medical Center, New York, New York. Electronic address: msm10@cumc.columbia.edu.
³ Department of Medicine, Division of Geriatric Medicine and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Editorial

Chris L Schaich et al. JACC Heart Fail. 2019 Feb.

. 2019 Feb;7(2):129-131.

doi: 10.1016/j.jchf.2018.12.014.

¹ Department of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
² Clinical Cardiovascular Research Laboratory for the Elderly, Columbia University Irving Medical Center, New York, New York. Electronic address: msm10@cumc.columbia.edu.
³ Department of Medicine, Division of Geriatric Medicine and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

No abstract available

Keywords: Alzheimer; amyloid; transthyretin.

Comment on

Cardiac Abnormalities in Alzheimer Disease: Clinical Relevance Beyond Pathophysiological Rationale and Instrumental Findings?
Sanna GD, Nusdeo G, Piras MR, Forteleoni A, Murru MR, Saba PS, Dore S, Sotgiu G, Parodi G, Ganau A. Sanna GD, et al. JACC Heart Fail. 2019 Feb;7(2):121-128. doi: 10.1016/j.jchf.2018.10.022. JACC Heart Fail. 2019. PMID: 30704603

1. Plassman BL, Langa KM, Fisher GG et al. Prevalence of dementia in the United States: the aging, demographics, and memory study. Neuroepidemiology 2007;29:125–32. - PMC - PubMed
1. Gonzalez-Lopez E, Gallego-Delgado M, Guzzo-Merello G et al. Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction. Eur Heart J 2015;36:2585–94. - PubMed
1. Ruberg FL, Berk JL. Transthyretin (TTR) cardiac amyloidosis. Circulation 2012;126(10):1286–1300. - PMC - PubMed
1. Calik AN, Ozcan KS, Yuksel G et al. Altered diastolic function and aortic stiffness in Alzheimer’s disease. Clin Interv Aging 2014;9:1115–21. - PMC - PubMed
1. Jin WS, Bu XL, Wang YR et al. Reduced Cardiovascular Functions in Patients with Alzheimer’s Disease. J Alzheimers Dis 2017;58:919–925. - PubMed