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Case Reports
. 2018 Sep 7;4(1):10-14.
doi: 10.1016/j.adro.2018.08.025. eCollection 2019 Jan-Mar.

Radiation-Induced Colitis in a Pancreatic Cancer Patient With a Germline BRCA2 Mutation: A Case Report

Adam R Wolfe  1 , Rishi Jain  2 , Timothy M Pawlik  3 , Jon Walker  4 , Terence M Williams  1
Affiliations
Case Reports

Radiation-Induced Colitis in a Pancreatic Cancer Patient With a Germline BRCA2 Mutation: A Case Report

Adam R Wolfe et al. Adv Radiat Oncol. .
No abstract available

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Figures

Figure 1
Figure 1
Axial view of computed tomography scan of the abdomen before chemoradiation therapy. Pancreatic tumor abutted but did not encase the hepatic artery, portal splenic confluence, or superior mesenteric artery.
Figure 2
Figure 2
Radiation treatment plan (planned for a total dose of 55 Gy in 25 fractions with concurrent 5-flourouracil). (A) Axial slice showing radiation dose overlapping the transverse colon. (B) Coronal image of radiation plan. Large areas of overlap between treatment planning target volume and large bowel.
Figure 3
Figure 3
Coronal view from computed tomography scan of the abdomen after radiation therapy. Note pancolonic wall thickening with adjacent inflammatory changes compatible with an acute inflammatory colitis.
Figure 4
Figure 4
Colonoscopy showing mucosa with punctate hemorrhages, ulceration, and increased friability with contact.
See this image and copyright information in PMC

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