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Review
. 2019 Jan-Mar;62(1):125-128.
doi: 10.4103/IJPM.IJPM_761_17.

Lymphoepithelioma-like carcinoma of breast: A case report and review of the literature

María Tereza Nieto-Coronel  1 , Víctor Manuel Perez-Sanchez  2 , Jessica Elizabeth Salazar-Campos  3 , Raul Diaz-Molina  4 , Claudia Haydee Arce-Salinas  1
Affiliations
Review

Lymphoepithelioma-like carcinoma of breast: A case report and review of the literature

María Tereza Nieto-Coronel et al. Indian J Pathol Microbiol. 2019 Jan-Mar.

Abstract

Lymphoepithelioma is a rare clinical entity, first was described in nasopharynx, and have been reported in another organs. Lymphoepithelioma-like carcinoma (LEC) of the breast is an undifferentiated carcinoma. Approximately 32 cases have been described, and differential diagnoses include primary breast lymphoma and medullary carcinoma. We present a 57-year-old woman, diagnosed with LEC of the breast, treated with mastectomy, followed by adjuvant chemotherapy, radiotherapy, and hormone therapy, with a disease-free interval of 2 years. There is scarce evidence related to the best treatment choice in this histological type.

Keywords: Breast; Epstein–Barr virus; lymphoepithelioma-like carcinoma; lymphoma.

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