Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
- PMID: 30709027
- PMCID: PMC6384601
- DOI: 10.3390/molecules24030519
Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review
Abstract
Recent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) system integration and measurement set-ups. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed.
Keywords: aptamers; biomaterials; biophotonics; biosensors; integrated optical sensors; lab-on-a-chip; optical sensor; ring resonators; silicon photonics.
Conflict of interest statement
The authors declare no conflict of interest.
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