Weight Management in Obstructive Sleep Apnea: Medical and Surgical Options
- PMID: 30709529
- DOI: 10.1016/j.jsmc.2018.10.002
Weight Management in Obstructive Sleep Apnea: Medical and Surgical Options
Abstract
Obesity plays a pivotal role in the pathogenesis of obstructive sleep apnea (OSA) and as an exacerbating factor of OSA. Given the interlinking relationship of obesity and OSA, treatment of obesity is fundamental in the management of OSA. Weight loss of 7% to 11% significantly improves OSA with remission seen with greater weight loss. Weight loss also ameliorates the constellation of other obesity-related metabolic conditions, reducing the overall cardiovascular risk in an obese person with OSA. This article discusses specific weight loss interventions effective in improving OSA, including lifestyle interventions with dietary modification and physical activity, pharmacotherapy, and bariatric surgery.
Keywords: Asians; Bariatric surgery; Obesity; Obstructive sleep apnea; Pharmacotherapy; Weight loss.
Copyright © 2018 Elsevier Inc. All rights reserved.
Similar articles
-
Surgical and Nonsurgical Weight Loss for Patients with Obstructive Sleep Apnea.Otolaryngol Clin North Am. 2020 Jun;53(3):409-420. doi: 10.1016/j.otc.2020.02.003. Epub 2020 Apr 23. Otolaryngol Clin North Am. 2020. PMID: 32334866 Review.
-
Improvement in Obstructive Sleep Apnea With Weight Loss is Dependent on Body Position During Sleep.Sleep. 2017 May 1;40(5). doi: 10.1093/sleep/zsx047. Sleep. 2017. PMID: 28444355 Clinical Trial.
-
Surgical vs conventional therapy for weight loss treatment of obstructive sleep apnea: a randomized controlled trial.JAMA. 2012 Sep 19;308(11):1142-9. doi: 10.1001/2012.jama.11580. JAMA. 2012. PMID: 22990273 Clinical Trial.
-
Obesity and obstructive sleep apnea--clinical significance of weight loss.Sleep Med Rev. 2013 Oct;17(5):321-9. doi: 10.1016/j.smrv.2012.08.002. Epub 2012 Oct 16. Sleep Med Rev. 2013. PMID: 23079209 Review.
-
Interactions between obesity and obstructive sleep apnea: implications for treatment.Chest. 2010 Mar;137(3):711-9. doi: 10.1378/chest.09-0360. Chest. 2010. PMID: 20202954 Free PMC article. Review.
Cited by
-
Effects of Weight Loss on Obstructive Sleep Apnea Severity. Ten-Year Results of the Sleep AHEAD Study.Am J Respir Crit Care Med. 2021 Jan 15;203(2):221-229. doi: 10.1164/rccm.201912-2511OC. Am J Respir Crit Care Med. 2021. PMID: 32721163 Free PMC article. Clinical Trial.
-
Oropharyngeal rhabdomyoma: the cause of severe sleep apnoea?BMJ Case Rep. 2020 Feb 9;13(2):e230949. doi: 10.1136/bcr-2019-230949. BMJ Case Rep. 2020. PMID: 32041754 Free PMC article.
-
Obesity as a risk factor for poor outcome in COVID-19-induced lung injury: the potential role of undiagnosed obstructive sleep apnoea.Br J Anaesth. 2020 Aug;125(2):e262-e263. doi: 10.1016/j.bja.2020.04.078. Epub 2020 May 1. Br J Anaesth. 2020. PMID: 32439072 Free PMC article. No abstract available.
-
[Arousal characteristics in different OSAHS populations].Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Apr;36(4):278-285. doi: 10.13201/j.issn.2096-7993.2022.04.008. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022. PMID: 35511620 Free PMC article. Chinese.
-
Body mass index as a predictor of the outcomes of acute clozapine toxicity: a cross-sectional study.Toxicol Res (Camb). 2023 Jun 30;12(4):599-607. doi: 10.1093/toxres/tfad051. eCollection 2023 Aug. Toxicol Res (Camb). 2023. PMID: 37663813 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical