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Review
. 2019 Mar;33(1):197-212.
doi: 10.1016/j.idc.2018.10.012.

New Tools to Test Stool: Managing Travelers' Diarrhea in the Era of Molecular Diagnostics

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Review

New Tools to Test Stool: Managing Travelers' Diarrhea in the Era of Molecular Diagnostics

Eric J Eckbo et al. Infect Dis Clin North Am. 2019 Mar.

Abstract

Travelers' diarrhea affects up to 60% of visitors to tropical and subtropical regions. Although symptoms are generally self-limited, some infections are associated with significant morbidity and occasional mortality. Newer molecular diagnostic techniques allow for highly sensitive, specific, and expeditious testing of a wide range of potential pathogens. Identification of the causative pathogen of travelers' diarrhea allows for targeted therapy and management and a reduction in empiric broad-spectrum coverage.

Keywords: Diagnostics; Enteric infections; Enterotoxigenic Escherichia coli; Molecular testing; Multiplex PCR; Shigella; Travelers’ diarrhea.

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