Increased Fragility Fracture Rates in Older Men With Osteomyelitis
- PMID: 30715288
- PMCID: PMC6743834
- DOI: 10.1093/cid/ciz077
Increased Fragility Fracture Rates in Older Men With Osteomyelitis
Abstract
In this study, we evaluated fracture incidence over a 10-year period among men with and without osteomyelitis from the Veterans Aging Cohort Study. Fracture incidence was significantly higher among those with osteomyelitis at all osteoporotic fracture sites after adjusting for key related risk factors. Future prospective studies are warranted.
Keywords: fracture incidence; inflammatory bone loss; osteomyelitis.
© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
References
-
- Claro T, Widaa A, McDonnell C, Foster TJ, O’Brien FJ, Kerrigan SW. Staphylococcus aureus protein A binding to osteoblast tumour necrosis factor receptor 1 results in activation of nuclear factor kappa B and release of interleukin-6 in bone infection. Microbiology 2013; 159:147–54. - PubMed
-
- Gelfand MS, Cleveland KO, Heck RK, Goswami R. Pathological fracture in acute osteomyelitis of long bones secondary to community-acquired methicillin-resistant Staphylococcus aureus: two cases and review of the literature. Am J Med Sci 2006; 332:357–60. - PubMed
-
- Belthur MV, Birchansky SB, Verdugo AA, et al. . Pathologic fractures in children with acute Staphylococcus aureus osteomyelitis. J Bone Joint Surg Am 2012; 94:34–42. - PubMed
-
- Fultz SL, Skanderson M, Mole LA, et al. . Development and verification of a “virtual” cohort using the National VA Health Information System. Med Care 2006; 44:S25–30. - PubMed
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