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. 2019 Mar 18;47(5):2701.

doi: 10.1093/nar/gkz065.

RNase H sequence preferences influence antisense oligonucleotide efficiency

Łukasz J Kiełpiński¹, Peter H Hagedorn¹, Morten Lindow¹, Jeppe Vinther²

Affiliations

Affiliations

¹ Roche Pharmaceutical Discovery and Early Development, Therapeutic Modalities, Roche Innovation Center Copenhagen, Fremtidsvej 3, DK-2970 Hørsholm, Denmark.
² Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen N, Denmark.

PMID: 30715421
PMCID: PMC6412118
DOI: 10.1093/nar/gkz065

RNase H sequence preferences influence antisense oligonucleotide efficiency

Łukasz J Kiełpiński et al. Nucleic Acids Res. 2019.

. 2019 Mar 18;47(5):2701.

doi: 10.1093/nar/gkz065.

Authors

Łukasz J Kiełpiński¹, Peter H Hagedorn¹, Morten Lindow¹, Jeppe Vinther²

Affiliations

¹ Roche Pharmaceutical Discovery and Early Development, Therapeutic Modalities, Roche Innovation Center Copenhagen, Fremtidsvej 3, DK-2970 Hørsholm, Denmark.
² Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen N, Denmark.

PMID: 30715421
PMCID: PMC6412118
DOI: 10.1093/nar/gkz065

No abstract available

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Expression of concern for

RNase H sequence preferences influence antisense oligonucleotide efficiency.
Kielpinski LJ, Hagedorn PH, Lindow M, Vinther J. Kielpinski LJ, et al. Nucleic Acids Res. 2017 Dec 15;45(22):12932-12944. doi: 10.1093/nar/gkx1073. Nucleic Acids Res. 2017. PMID: 29126318 Free PMC article.

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