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Review
. 2019 May;156(7):1969-1978.
doi: 10.1053/j.gastro.2018.12.043. Epub 2019 Feb 1.

Pancreatitis in Children

Aliye Uc  1 , Sohail Z Husain  2
Affiliations
Review

Pancreatitis in Children

Aliye Uc et al. Gastroenterology. 2019 May.

Abstract

Acute, acute recurrent, and chronic forms of pancreatitis have been increasingly diagnosed in children in the past 2 decades. Risk factors in the pediatric group are broad and appear to be strikingly different compared with the adult cohort. However, the disease burden and impact on quality of life are surprisingly similar in children and adults. This review summarizes the definitions, epidemiology, risk factors, diagnosis, and management of pediatric pancreatitis, identifies features that are unique to the childhood-onset disease, identifies gaps, and proposes recommendations for future opportunities.

Keywords: Children; Diabetes; Exocrine Pancreatic Insufficiency; Genetic.

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Conflict of interest statement

Conflicts of interest

The authors disclose the following: Aliye Uc is a member of American Board of Pediatrics and sub-board of Pediatric Gastroenterology. Sohail Z. Husain owns equity in PrevCon.

Figures

Figure 1
Figure 1
Risk factors for AP, ARP, and CP in childhood., Figure shows the most common risk factors for AP (A), ARP (B), and CP (C) in children. HTG, hypertriglyceridemia; Meds, medications.
Figure 2
Figure 2
Imaging changes in pediatric CP. ERCP fluoroscopy image from a 10-year-old boy with hereditary pancreatitis (PRSS1 R122H mutation) shows irregular filling, stricture, and dilatation (up to 4.2 mm) of the main PD and its side branches. Image courtesy of Dr Simon Kao, Stead Family Children’s Hospital, University of Iowa, Iowa City, Iowa.
See this image and copyright information in PMC

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