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Review
. 1988 Dec;15(6):355-66.
doi: 10.2165/00003088-198815060-00001.

Clinical pharmacokinetics of doxycycline and minocycline

S Saivin  1 , G Houin
Affiliations
Review

Clinical pharmacokinetics of doxycycline and minocycline

S Saivin et al. Clin Pharmacokinet. 1988 Dec.

Abstract

Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.

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