[Intracranial meningiomas]

Abstract

Meningiomas are the most frequent intracranial non-glial tumours. They are derived from arachnoid cap cells and are classified according to WHO histology-based classification. The epigenetic technique DNA methylation profiling has shown improved prognostic value in comparison to the current WHO classification. Total surgical tumour removal is still golden standard in meningioma treatment with radiation as a supplement for WHO high-grade patients and inoperable patients. Efficient medical alternatives to surgery are not yet available, but future research may provide new strategies to be explored.