Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Physiology, Thyroid Function

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Physiology, Thyroid Function

Maggie Armstrong et al.
Free Books & Documents

Excerpt

The thyroid is an endocrine gland. Its location is in the inferior, anterior neck, responsible for the formation and secretion of thyroid hormones and iodine homeostasis within the human body. The thyroid produces approximately 90% inactive thyroid hormone, or thyroxine (T4), and 10% active thyroid hormone, or triiodothyronine (T3). Inactive thyroid hormone is converted peripherally to either activated thyroid hormone or an alternative inactive thyroid hormone.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Maggie Armstrong declares no relevant financial relationships with ineligible companies.

Disclosure: Edinen Asuka declares no relevant financial relationships with ineligible companies.

Disclosure: Abbey Fingeret declares no relevant financial relationships with ineligible companies.

References

    1. Coste AH, Lofgren DH, Shermetaro C. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Jun 30, Branchial Cleft Cyst. - PubMed
    1. Choi JH, Cho JH, Kim JH, Yoo EG, Kim GH, Yoo HW. Variable Clinical Characteristics and Molecular Spectrum of Patients with Syndromes of Reduced Sensitivity to Thyroid Hormone: Genetic Defects in the THRB and SLC16A2 Genes. Horm Res Paediatr. 2018;90(5):283-290. - PubMed
    1. Yasoda A. [Secondary osteoporosis. Hyperthyroidism.]. Clin Calcium. 2018;28(12):1619-1625. - PubMed
    1. Duran İD, Gülçelik NE, Bulut B, Balcı Z, Berker D, Güler S. Differences in Calcium Metabolism and Thyroid Physiology After Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Obes Surg. 2019 Feb;29(2):705-712. - PubMed
    1. Maradonna F, Carnevali O. Lipid Metabolism Alteration by Endocrine Disruptors in Animal Models: An Overview. Front Endocrinol (Lausanne) 2018;9:654. - PMC - PubMed

Publication types

LinkOut - more resources