Nifedipine
- PMID: 30725737
- Bookshelf ID: NBK537052
Nifedipine
Excerpt
Nifedipine is a dihydropyridine calcium channel blocker approved for the treatment of chronic stable angina and hypertension. This activity outlines the pharmacological profile of nifedipine, including indications, mechanism of action, routes of administration, and toxicity. Off-label uses are also reviewed to provide context for broader clinical applications. Attention is given to key drug-drug interactions, pharmacokinetics, and monitoring requirements to guide safe and effective prescribing. Significant adverse effects and contraindications are discussed to support risk assessment and therapeutic decision-making. Understanding these elements enables clinicians to tailor therapy to the patient's specific cardiovascular needs and comorbidities, thereby optimizing treatment outcomes.
Copyright © 2025, StatPearls Publishing LLC.
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