Ramipril
- PMID: 30725804
- Bookshelf ID: NBK537119
Ramipril
Excerpt
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension and prevent heart failure progression in patients with a history of myocardial infarction. This medication is also indicated for reducing the risk of myocardial infarction, stroke, and mortality in patients older than 55 who are at high risk for atherosclerotic disease and severe adverse cardiac events. Ramipril suppresses angiotensin II synthesis, reducing sympathetic activity and sodium and water reabsorption in the kidneys. The resulting vasodilation reduces blood pressure.
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