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Book

Hypoxic Brain Injury

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Hypoxic Brain Injury

Myriam Lacerte et al.
Free Books & Documents

Excerpt

The brain consumes much energy compared to its weight and size. It is highly metabolically active and exquisitely sensitive to hypoxia and hypoperfusion. Cellular injury can begin within minutes, and permanent brain injury follows if prompt intervention does not occur. Therefore, it is critical to understand the clinical presentation, pathophysiology, and management options.

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Conflict of interest statement

Disclosure: Myriam Lacerte declares no relevant financial relationships with ineligible companies.

Disclosure: Angela Hays Shapshak declares no relevant financial relationships with ineligible companies.

Disclosure: Fassil Mesfin declares no relevant financial relationships with ineligible companies.

References

    1. Arora S, Tantia P. Physiology of Oxygen Transport and its Determinants in Intensive Care Unit. Indian J Crit Care Med. 2019 Sep;23(Suppl 3):S172-S177. - PMC - PubMed
    1. Howell K, Grill E, Klein AM, Straube A, Bender A. Rehabilitation outcome of anoxic-ischaemic encephalopathy survivors with prolonged disorders of consciousness. Resuscitation. 2013 Oct;84(10):1409-15. - PubMed
    1. Laver S, Farrow C, Turner D, Nolan J. Mode of death after admission to an intensive care unit following cardiac arrest. Intensive Care Med. 2004 Nov;30(11):2126-8. - PubMed
    1. Lascarrou JB, Merdji H, Le Gouge A, Colin G, Grillet G, Girardie P, Coupez E, Dequin PF, Cariou A, Boulain T, Brule N, Frat JP, Asfar P, Pichon N, Landais M, Plantefeve G, Quenot JP, Chakarian JC, Sirodot M, Legriel S, Letheulle J, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Giraudeau B, Reignier J, CRICS-TRIGGERSEP Group Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm. N Engl J Med. 2019 Dec 12;381(24):2327-2337. - PubMed
    1. Gräsner JT, Lefering R, Koster RW, Masterson S, Böttiger BW, Herlitz J, Wnent J, Tjelmeland IB, Ortiz FR, Maurer H, Baubin M, Mols P, Hadžibegović I, Ioannides M, Škulec R, Wissenberg M, Salo A, Hubert H, Nikolaou NI, Lóczi G, Svavarsdóttir H, Semeraro F, Wright PJ, Clarens C, Pijls R, Cebula G, Correia VG, Cimpoesu D, Raffay V, Trenkler S, Markota A, Strömsöe A, Burkart R, Perkins GD, Bossaert LL, EuReCa ONE Collaborators EuReCa ONE-27 Nations, ONE Europe, ONE Registry: A prospective one month analysis of out-of-hospital cardiac arrest outcomes in 27 countries in Europe. Resuscitation. 2016 Aug;105:188-95.

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