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Book

Histology, Skin

Sanjay Agarwal  1 , Karthik Krishnamurthy  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Free Books & Documents
Book

Histology, Skin

Sanjay Agarwal et al.
Free Books & Documents

Excerpt

Skin is part of the integumentary system and considered to be the largest organ of the human body. There are three main layers of skin: the epidermis, the dermis, and the hypodermis (subcutaneous fat). The focus of this topic is on the epidermal and dermal layers of skin. Skin appendages such as sweat glands, hair follicles, and sebaceous glands are reviewed in-depth elsewhere.

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Conflict of interest statement

Disclosure: Sanjay Agarwal declares no relevant financial relationships with ineligible companies.

Disclosure: Karthik Krishnamurthy declares no relevant financial relationships with ineligible companies.

References

    1. Brown TM, Krishnamurthy K. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. May 1, Histology, Hair and Follicle. - PubMed
    1. Murphrey MB, Miao JH, Zito PM. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2022. Nov 14, Histology, Stratum Corneum. - PubMed
    1. Sahle FF, Gebre-Mariam T, Dobner B, Wohlrab J, Neubert RH. Skin diseases associated with the depletion of stratum corneum lipids and stratum corneum lipid substitution therapy. Skin Pharmacol Physiol. 2015;28(1):42-55. - PubMed
    1. Xia J, Wang Y, Li F, Wang J, Mu Y, Mei X, Li X, Zhu W, Jin X, Yu K. Expression of microphthalmia transcription factor, S100 protein, and HMB-45 in malignant melanoma and pigmented nevi. Biomed Rep. 2016 Sep;5(3):327-331. - PMC - PubMed
    1. Kanitakis J. Anatomy, histology and immunohistochemistry of normal human skin. Eur J Dermatol. 2002 Jul-Aug;12(4):390-9; quiz 400-1. - PubMed

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