Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Feb 5;29(2):236-238.
doi: 10.1016/j.cmet.2019.01.009.

Host Control of Tumor Feeding: Autophagy Holds the Key

Anthony Venida  1 , Rushika M Perera  2
Affiliations
Free article
Comment

Host Control of Tumor Feeding: Autophagy Holds the Key

Anthony Venida et al. Cell Metab. .
Free article

Abstract

Cancer cells are dependent on functional autophagy both within their cytoplasm and systemically in the host to maintain growth. How systemic autophagy directly contributes to tumor growth remains unclear. In a study published in Nature, Poillet-Perez et al. (2018) show that host autophagy helps to maintain the levels of circulating arginine that feed tumor growth.

PubMed Disclaimer

Comment on

  • Autophagy maintains tumour growth through circulating arginine.
    Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E. Poillet-Perez L, et al. Nature. 2018 Nov;563(7732):569-573. doi: 10.1038/s41586-018-0697-7. Epub 2018 Nov 14. Nature. 2018. PMID: 30429607 Free PMC article.

Publication types

LinkOut - more resources