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Comment
. 2019 Feb 5;29(2):243-245.
doi: 10.1016/j.cmet.2019.01.012.

Regulatory T Cells under the Mercy of Mitochondria

Mrinmoy Das  1 , Fawaz Alzaid  2 , Jagadeesh Bayry  3
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Free article
Comment

Regulatory T Cells under the Mercy of Mitochondria

Mrinmoy Das et al. Cell Metab. .
Free article

Abstract

Mitochondria, the powerhouse of the cell, known for producing energy through oxidative phosphorylation and the Krebs cycle, continue gaining notoriety for roles beyond bioenergetics. Recently in Nature, Weinberg et al. (2019) reported that mitochondrial complex III is indispensable for suppressive function of regulatory T cells, thus highlighting the importance of mitochondria in immune tolerance.

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