Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jan 27:12:1178224218823511.
doi: 10.1177/1178224218823511. eCollection 2019.

Reflections on palliative sedation

Reflections on palliative sedation

Robert Twycross. Palliat Care. .

Abstract

'Palliation sedation' is a widely used term to describe the intentional administration of sedatives to reduce a dying person's consciousness to relieve intolerable suffering from refractory symptoms. Research studies generally focus on either 'continuous sedation until death' or 'continuous deep sedation'. It is not always clear whether instances of secondary sedation (i.e. caused by specific symptom management) have been excluded. Continuous deep sedation is controversial because it ends a person's 'biographical life' (the ability to interact meaningfully with other people) and shortens 'biological life'. Ethically, continuous deep sedation is an exceptional last resort measure. Studies suggest that continuous deep sedation has become 'normalized' in some countries and some palliative care services. Of concern is the dissonance between guidelines and practice. At the extreme, there are reports of continuous deep sedation which are best described as non-voluntary (unrequested) euthanasia. Other major concerns relate to its use for solely non-physical (existential) reasons, the under-diagnosis of delirium and its mistreatment, and not appreciating that unresponsiveness is not the same as unconsciousness (unawareness). Ideally, a multiprofessional palliative care team should be involved before proceeding to continuous deep sedation. Good palliative care greatly reduces the need for continuous deep sedation.

Keywords: Palliative sedation; continuous deep sedation; continuous sedation until death.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

References

    1. Ventafridda V, Ripamonti C, de Conno F, et al. Symptom prevalence and control during cancer patients’ last days of life. J Palliat Care 1990; 6: 7–11. - PubMed
    1. Mount B. A final crescendo of pain? J Palliat Care 1990; 6: 5–6. - PubMed
    1. Roy DJ. Need they sleep before they die? J Palliat Care 1990; 6: 3–4. - PubMed
    1. Papavasiliou E, Payne S, Brearley S, et al. Continuous sedation (CS) until death: mapping the literature by bibliometric analysis. J Pain Symptom Manage 2013; 45: 1073–1082.e10. - PubMed
    1. Papavasiliou ES, Brearley SG, Seymour JE, et al. From sedation to continuous sedation until death: how has the conceptual basis of sedation in end-of-life care changed over time? J Pain Symptom Manage 2013; 46: 691–706. - PubMed

LinkOut - more resources