Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019:1914:331-342.
doi: 10.1007/978-1-4939-8997-3_18.

Murine Models of Bone Sarcomas

Camille Jacques  1 , Nathalie Renema  2 , Benjamin Ory  1 , Carl R Walkley  3 , Agamemnon E Grigoriadis  4 , Dominique Heymann  5
Affiliations

Murine Models of Bone Sarcomas

Camille Jacques et al. Methods Mol Biol. 2019.

Abstract

This chapter describes the procedures for inducing bone sarcoma in mice. Two models based on inoculation of cancer cells in paraosseous and intraosseous site will be described. In addition to providing technical aspects of anesthesia and surgical options, key information of cell preparation and postoperative follow-up will be discussed.

Keywords: Bone sarcoma; Cell-injection; Chondrosarcoma; Ewing sarcoma; Genetically-engineered mouse models; Murine preclinical models; Osteosarcoma.

PubMed Disclaimer

MeSH terms

LinkOut - more resources