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Review
. 2019 Jan;10(1):37-61.
doi: 10.4155/tde-2018-0051.

Exosomes: fighting cancer with cancer

Hanin Alyamani  1 , Mohammad A Obeid  2 , Rothwelle J Tate  1 , Valerie A Ferro  1
Affiliations
Review

Exosomes: fighting cancer with cancer

Hanin Alyamani et al. Ther Deliv. 2019 Jan.

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] Ther Deliv. 2019 Feb;10(2):133. doi: 10.4155/tde-2018-0051c1. Ther Deliv. 2019. PMID: 30729885 No abstract available.

Abstract

Exosomes are nanovesicles secreted by many cells, including cancer cells. Extensive research has been carried out to validate potential applications of exosomes and to evaluate their efficiency in a wide range of diseases, including cancer. The current knowledge on the origin, biogenesis and composition of exosomes is described. This review then focuses on the use of exosomes in cancer diagnostics and therapeutics.

Keywords: angiogenesis; cancer; diagnostic; exosomes; immune system; immunosuppression; miRNA; nucleic acid; progression; therapeutic.

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