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Review
. 1988 Jul-Dec:9:31-88.
doi: 10.1007/BF03160355.

Acidosis and ischemic brain damage

B K Siesjö  1
Affiliations
Review

Acidosis and ischemic brain damage

B K Siesjö. Neurochem Pathol. 1988 Jul-Dec.

Abstract

It is now widely accepted that acidosis is an important component of the pathogenetic events that lead to ischemic brain damage. The objective with this article is to recall the evolution of the concept, to describe the conditions under which tissue acidosis arises and causes enhanced brain damage, and to probe into the cellular and molecular mechanisms involved.

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