Defects in adenosine metabolism identified in ALS
- PMID: 30733617
- DOI: 10.1038/s41582-019-0147-7
Defects in adenosine metabolism identified in ALS
Comment on
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Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.Brain. 2019 Mar 1;142(3):586-605. doi: 10.1093/brain/awy353. Brain. 2019. PMID: 30698736 Free PMC article.
References
Original article
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- Allen, S. P. et al. Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis. Brain https://doi.org/10.1093/brain/awy353 (2019) - DOI - PubMed
Further reading
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- Allen, S. P. et al. Superoxide dismutase 1 mutation in a cellular model of amyotrophic lateral sclerosis shifts energy generation from oxidative phosphorylation to glycolysis. Neurobiol. Aging 35, 1499–1509 (2014) - DOI
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