Myeloid cells in the central nervous system: So similar, yet so different
- PMID: 30737356
- DOI: 10.1126/sciimmunol.aaw2841
Myeloid cells in the central nervous system: So similar, yet so different
Abstract
Dissection of the heterogeneity of CNS myeloid cells reveals functionally distinct subsets that govern encephalitogenic T cells. See related Research Article by Jordão et al.
Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
Comment on
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Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation.Sci Immunol. 2019 Jan 25;4(31):eaau8380. doi: 10.1126/sciimmunol.aau8380. Sci Immunol. 2019. PMID: 30679199
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Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation.Science. 2019 Jan 25;363(6425):eaat7554. doi: 10.1126/science.aat7554. Science. 2019. PMID: 30679343
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