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. 2019 Jan 28;7(2):269-271.
doi: 10.3889/oamjms.2019.090. eCollection 2019 Jan 30.

Efficacy of 10% Potassium Hydroxide Solution Versus 10% Salicylic Acid Ointment in Treatment of Molluscum Contagiosum - the Low - Cost Dermatologic Therapy in Vietnam

Sau Nguyen Huu  1   2 , Minh Nguyen Quang  1 , Thuong Nguyen Van  1   2 , Kiem Pham Cao  1 , Hien Do Thi Thu  1 , Lan Pham Thi  1   2 , Van Tran Cam  1 , My Le Huyen  1 , Khang Tran Hau  1   2 , Marco Gandolfi  3 , Francesca Satolli  3 , Claudio Feliciani  3 , Michael Tirant  3   4 , Aleksandra Vojvodic  5 , Torello Lotti  3
Affiliations

Efficacy of 10% Potassium Hydroxide Solution Versus 10% Salicylic Acid Ointment in Treatment of Molluscum Contagiosum - the Low - Cost Dermatologic Therapy in Vietnam

Sau Nguyen Huu et al. Open Access Maced J Med Sci. .

Abstract

Background: Molluscum contagiosum is a common viral disease primarily affecting children.

Aim: The objective is to compare the efficacy of 10% potassium hydroxide (KOH) solution versus 10% salicylic pomade in the treatment of molluscum contagiosum.

Methods: Clinical trials on 70 patients were randomised into 2 groups: 39 patients treated with 10% KOH solution and 31 patients treated with 10% salicylic pomade. The evaluation was based on the complete clearance of lesions, side effects and complications of the drug.

Results: The clearance of all lesions after 2, 4, 6, 8 weeks of treatment in both groups were 7.7%; 23.1%; 53.8%; 79.5% and 0%; 3.2%, 9.7% 22.6%, respectively (p < 0.05). Side effects were seen in both groups include burning (76.9% versus 19.4%; p < 0.05); redness (59% versus 14%; p < 0.01); desquamation (12.8% versus 19.3%; p < 0.05).

Conclusion: The efficacy of KOH solution in the treatment of MC was better than that of salicylic pomade and both products are safe, effective, and easy to apply at home.

Keywords: Molluscum contagiosum; Potassium Hydroxide; Salicylic pomade.

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Figures

Figure 1
Figure 1
A) 8-year-old girl after 2 days of treatment; B) Another child had excellent improvement after treatment by KOH solution
See this image and copyright information in PMC

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