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Editorial
. 2019 Mar 1;30(3):355-357.
doi: 10.1093/annonc/mdz042.

Searching for the needle in the haystack: deconvoluting the evolutionary dynamics of residual disease in human glioblastoma

S T C Shepherd  1 , K Litchfield  2 , S Turajlic  3
Affiliations
Editorial

Searching for the needle in the haystack: deconvoluting the evolutionary dynamics of residual disease in human glioblastoma

S T C Shepherd et al. Ann Oncol. .
No abstract available

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Figures

Figure 1.
Figure 1.
Residual disease in glioblastoma. (A) At surgery, only the primary tumour mass (red online) is removed (in dark grey the resection cavity). (B) However, infiltrative cells in the normal brain parenchyma (green online) and sub-ventricular zone (SVZ) (blue online) are left behind. (C) Residual glioblastoma cells infiltrated throughout the brain can give rise to relapse, both locally and distally. Reproduced this figure with permission from Spiteri et al. [2].
See this image and copyright information in PMC

Comment on

  • Evolutionary dynamics of residual disease in human glioblastoma.
    Spiteri I, Caravagna G, Cresswell GD, Vatsiou A, Nichol D, Acar A, Ermini L, Chkhaidze K, Werner B, Mair R, Brognaro E, Verhaak RGW, Sanguinetti G, Piccirillo SGM, Watts C, Sottoriva A. Spiteri I, et al. Ann Oncol. 2019 Mar 1;30(3):456-463. doi: 10.1093/annonc/mdy506. Ann Oncol. 2019. PMID: 30452544 Free PMC article.

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