Invasion by Force: The C. elegans Anchor Cell Leads the Way
- PMID: 30753832
- DOI: 10.1016/j.devcel.2019.01.024
Invasion by Force: The C. elegans Anchor Cell Leads the Way
Abstract
How cells breach basement membrane barriers remains an area of active research. In this issue of Developmental Cell, Kelley et al. (2019) reveal that the C. elegans anchor cell uses physical force to breach basement membrane in the absence of matrix metalloproteases during its developmental invasion.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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Adaptive F-Actin Polymerization and Localized ATP Production Drive Basement Membrane Invasion in the Absence of MMPs.Dev Cell. 2019 Feb 11;48(3):313-328.e8. doi: 10.1016/j.devcel.2018.12.018. Epub 2019 Jan 24. Dev Cell. 2019. PMID: 30686527 Free PMC article.
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