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. 2019 Feb 11;48(3):287-288.
doi: 10.1016/j.devcel.2019.01.024.

Invasion by Force: The C. elegans Anchor Cell Leads the Way

Savvas Nikolaou  1 , Laura M Machesky  2
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Invasion by Force: The C. elegans Anchor Cell Leads the Way

Savvas Nikolaou et al. Dev Cell. .
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Abstract

How cells breach basement membrane barriers remains an area of active research. In this issue of Developmental Cell, Kelley et al. (2019) reveal that the C. elegans anchor cell uses physical force to breach basement membrane in the absence of matrix metalloproteases during its developmental invasion.

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