An increase in reports of acute flaccid paralysis (AFP) in the United Kingdom, 1 January 2018-21 January 2019: early findings
- PMID: 30755296
- PMCID: PMC6373064
- DOI: 10.2807/1560-7917.ES.2019.24.6.1900093
An increase in reports of acute flaccid paralysis (AFP) in the United Kingdom, 1 January 2018-21 January 2019: early findings
Abstract
During 2018, the United Kingdom experienced an increase in reports of cases of acute flaccid paralysis (AFP). As at 21 January 2019, 40 cases had been identified with a peak in October 2018. The increase was temporally associated with an upsurge in enterovirus (EV) D68 activity. Enterovirus was detected in 15 cases, mainly from respiratory tract samples; nine were typed as EV-D68. A national task force has been established and investigations are ongoing.
Keywords: Acute flaccid paralysis; EV-D68; United Kingdom; acute flaccid myelitis; enterovirus D68; public health.
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References
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- CDC acute flaccid myelitis case definition https://wwwn.cdc.gov/nndss/conditions/acute-flaccid-myelitis/case-defini...
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- Knoester M, Helfferich J, Poelman R, Van Leer-Buter C, Brouwer OF, Niesters HGM, 2016 EV-D68 AFM Working Group Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview. Pediatr Infect Dis J. 2019;38(1):16-21. 10.1097/INF.0000000000002188 - DOI - PMC - PubMed
-
- Williams CJ, Thomas RH, Pickersgill TP, Lyons M, Lowe G, Stiff RE, et al. Cluster of atypical adult Guillain-Barré syndrome temporally associated with neurological illness due to EV-D68 in children, South Wales, United Kingdom, October 2015 to January 2016. Euro Surveill. 2016;21(4):30119. 10.2807/1560-7917.ES.2016.21.4.30119 - DOI - PubMed
-
- Chong PF, Kira R, Mori H, Okumura A, Torisu H, Yasumoto S, et al. Acute Flaccid Myelitis Collaborative Study Investigators Clinical Features of Acute Flaccid Myelitis Temporally Associated With an Enterovirus D68 Outbreak: Results of a Nationwide Survey of Acute Flaccid Paralysis in Japan, August-December 2015. Clin Infect Dis. 2018;66(5):653-64. 10.1093/cid/cix860 - DOI - PMC - PubMed
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