Quantifying and Interpreting the Association between Early-Life Gut Microbiota Composition and Childhood Obesity

Shirin Moossavi^{1

2

3

4}, Meghan B Azad^{2

3}

Affiliations

¹ Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada shirin.moossavi@gmail.com.
² Children's Hospital Research Institute of Manitoba, Pediatrics and Child Health, Winnipeg, Manitoba, Canada.
³ Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Winnipeg, Manitoba, Canada.
⁴ Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

PMID: 30755514
PMCID: PMC6372801
DOI: 10.1128/mBio.02787-18

Comment

Quantifying and Interpreting the Association between Early-Life Gut Microbiota Composition and Childhood Obesity

Shirin Moossavi et al. mBio. 2019.

. 2019 Feb 12;10(1):e02787-18.

doi: 10.1128/mBio.02787-18.

Authors

Shirin Moossavi^{1

2

3

4}, Meghan B Azad^{2

3}

Affiliations

¹ Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada shirin.moossavi@gmail.com.
² Children's Hospital Research Institute of Manitoba, Pediatrics and Child Health, Winnipeg, Manitoba, Canada.
³ Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Winnipeg, Manitoba, Canada.
⁴ Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

PMID: 30755514
PMCID: PMC6372801
DOI: 10.1128/mBio.02787-18

No abstract available

Keywords: infant; microbiota; obesity.

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Comment in

Reply to Moossavi and Azad, "Quantifying and Interpreting the Association between Early-Life Gut Microbiota Composition and Childhood Obesity".
Stanislawski MA, Dabelea D, Wagner BD, Iszatt N, Dahl C, Sontag MK, Knight R, Lozupone CA, Eggesbø M. Stanislawski MA, et al. mBio. 2019 Feb 12;10(1):e00047-19. doi: 10.1128/mBio.00047-19. mBio. 2019. PMID: 30755504 Free PMC article. No abstract available.

Comment on

Gut Microbiota in the First 2 Years of Life and the Association with Body Mass Index at Age 12 in a Norwegian Birth Cohort.
Stanislawski MA, Dabelea D, Wagner BD, Iszatt N, Dahl C, Sontag MK, Knight R, Lozupone CA, Eggesbø M. Stanislawski MA, et al. mBio. 2018 Oct 23;9(5):e01751-18. doi: 10.1128/mBio.01751-18. mBio. 2018. PMID: 30352933 Free PMC article.

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Haddad EN, Sugino KY, Kerver JM, Paneth N, Comstock SS. Haddad EN, et al. Curr Res Physiol. 2021;4:94-102. doi: 10.1016/j.crphys.2021.03.004. Epub 2021 Mar 26. Curr Res Physiol. 2021. PMID: 34136830 Free PMC article.
Metabolomic and Metataxonomic Fingerprinting of Human Milk Suggests Compositional Stability over a Natural Term of Breastfeeding to 24 Months.
Shenker NS, Perdones-Montero A, Burke A, Stickland S, McDonald JAK, Alexander-Hardiman K, Flanagan J, Takats Z, Cameron SJS. Shenker NS, et al. Nutrients. 2020 Nov 11;12(11):3450. doi: 10.3390/nu12113450. Nutrients. 2020. PMID: 33187120 Free PMC article.
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Min L, Ablitip A, Wang R, Luciana T, Wei M, Ma X. Min L, et al. Nutrients. 2024 Apr 5;16(7):1070. doi: 10.3390/nu16071070. Nutrients. 2024. PMID: 38613103 Free PMC article.
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Administration of Exogenous Melatonin Improves the Diurnal Rhythms of the Gut Microbiota in Mice Fed a High-Fat Diet.
Yin J, Li Y, Han H, Ma J, Liu G, Wu X, Huang X, Fang R, Baba K, Bin P, Zhu G, Ren W, Tan B, Tosini G, He X, Li T, Yin Y. Yin J, et al. mSystems. 2020 May 19;5(3):e00002-20. doi: 10.1128/mSystems.00002-20. mSystems. 2020. PMID: 32430404 Free PMC article.

References

1. Stanislawski MA, Dabelea D, Wagner BD, Iszatt N, Dahl C, Sontag MK, Knight R, Lozupone CA, Eggesbo M. 2018. Gut microbiota in the first 2 years of life and the association with body mass index at age 12 in a Norwegian birth cohort. mBio 9:e01751-18. doi:10.1128/mBio.01751-18. - DOI - PMC - PubMed
1. Azad MB, Vehling L, Chan D, Klopp A, Nickel NC, McGavock JM, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Taylor MS, Lefebvre DL, Sears MR, Subbarao P, on behalf of the CHILD Study Investigators. 2018. Infant feeding and weight gain: separating breast milk from breastfeeding and formula from food. Pediatrics 142:e20181092. doi:10.1542/peds.2018-1092. - DOI - PubMed
1. Kumar S, Kelly AS. 2017. Review of childhood obesity: from epidemiology, etiology, and comorbidities to clinical assessment and treatment. Mayo Clin Proc 92:251–265. doi:10.1016/j.mayocp.2016.09.017. - DOI - PubMed
1. Bridgman SL, Azad MB, Persaud RR, Chari RS, Becker AB, Sears MR, Mandhane PJ, Turvey SE, Subbarao P, Haqq AM, Kozyrskyj AL. 2018. Impact of maternal pre-pregnancy overweight on infant overweight at 1 year of age: associations and sex-specific differences. Pediatr Obes 13:579–589. doi:10.1111/ijpo.12291. - DOI - PubMed
1. Azad MB, Timpson N, Becker A, Mandhane P, Turvey S, Moraes T, Lefebvre D, Subbarao P, Sears M, Hinde K. 2018. More milk for daughers? Sex-differentiated breastfeeding in two birth cohorts. Breastfeed Med 13:A11. doi:10.1089/bfm.2018.29100.abstracts. - DOI

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Quantifying and Interpreting the Association between Early-Life Gut Microbiota Composition and Childhood Obesity

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Quantifying and Interpreting the Association between Early-Life Gut Microbiota Composition and Childhood Obesity

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