Recent advances in managing and understanding Klinefelter syndrome
- PMID: 30755791
- PMCID: PMC6352920
- DOI: 10.12688/f1000research.16747.1
Recent advances in managing and understanding Klinefelter syndrome
Abstract
Klinefelter syndrome can present as a wide spectrum of clinical manifestations at various stages in life, making it a chromosomal disorder with no standardized set of guidelines for appropriate management. Understanding the genetic and hormonal causes of this syndrome can allow physicians to treat each patient on a more individualized basis. The timing of diagnosis and degree of symptoms can guide management. This report will provide an updated review of the clinical presentation at various stages in life and the implications for management.
Keywords: 47; Klinefelter Syndrome; TESE; XXY; azoospermia; testis.
Conflict of interest statement
No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.
References
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- KLINEFELTER HF, REIFENSTEIN EC, ALBRIGHT F: Syndrome Characterized by Gynecomastia, Aspermatogenesis without A-Leydigism, and Increased Excretion of Follicle-Stimulating Hormone. J Clin Endocrinol Metab. 1942;2(11):615–27. 10.1210/jcem-2-11-615 - DOI
-
- Rajender A, Oates RD: Evaluation and Management of Klinefelter Syndrome.AUA Updat Ser.2018;37 Reference Source
-
- Bourke E, Herlihy A, Snow P, et al. : Klinefelter syndrome - a general practice perspective. Aust Fam Physician. 2014;43(1):38–41. - PubMed
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