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. 2018 Jun 26;5(6):000855.
doi: 10.12890/2018_000855. eCollection 2018.

Catatonia and Psychosis as Manifestations of Primary Sjögren's Syndrome

Steeve Neves Rosado  1 , Vera Silveira  1 , Ana Isabel Reis  1 , André Gordinho  1 , Carla Noronha  2
Affiliations

Catatonia and Psychosis as Manifestations of Primary Sjögren's Syndrome

Steeve Neves Rosado et al. Eur J Case Rep Intern Med. .

Abstract

Primary Sjögren's syndrome (SS) is a chronic, systemic autoimmune disease, most commonly presenting with sicca symptoms-xerostomia and xerophthalmia. Up to one-half of affected individuals also develop extra-glandular involvement. Early diagnosis is important to prevent further complications. This paper describes an atypical case of SS in a 21-year-old woman who presented first with neuropsychiatric symptoms and fever. She was diagnosed and treated for a presumed psychotic episode. However, because she remained febrile, a thorough investigation resulted in the challenging diagnosis of SS.

Learning points: Primary Sjögren's syndrome (SS) may be an under-recognized cause of central nervous system and neuropsychiatric involvement.Neuropsychiatric manifestations of primary SS can be variable.Patients may be treated incorrectly if the diagnosis is not rapidly established, so a clinical history and thorough examination are very important.

Keywords: Sjögren’s syndrome; catatonia; neuropsychiatric manifestations; psychosis.

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Conflict of interest statement

Conflicts of Interests: The Authors declare that there are no competing interests.

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