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Review
. 2019 Jan 13:2019:7919501.
doi: 10.1155/2019/7919501. eCollection 2019.

Neonatal Mortality in Hospitalized Chinese Population: A Meta-Analysis

Baoquan Zhang  1 , Yue Dai  2 , Hanqiang Chen  1 , Changyi Yang  1
Affiliations
Review

Neonatal Mortality in Hospitalized Chinese Population: A Meta-Analysis

Baoquan Zhang et al. Biomed Res Int. .

Abstract

Objective: In this meta-analysis, we aim to investigate the neonatal mortality in hospitalized Chinese population in the recent 20 years in China, which may provide basis for decreasing the neonatal mortality.

Methods: The merged mortality was estimated based on the random effect model, and subgroup analysis was performed for the gender, publication year, gestational age, and birth weight. Sensitivity analysis was utilized to evaluate the effects of research type and research quality on the effects.

Results: The neonatal mortality in eastern China was lower than that of the central and western China (2.3% versus 2.9; 2.3% versus 26.%). The mortality in neonates with a gestational age of 28-32 weeks (0.6%) was significantly higher than that of <28 weeks (0.1%), 32-37 weeks (0.3%), 37-42 weeks (0.4%), and >42 weeks (0.1%). The mortality in those with a body weight of 1.0-2.5 kg (0.3%) was significantly higher than that of 2.5-4.0 kg (0.2%) and >4.0 kg (0.0%). Sensitivity analysis revealed that the findings of meta-analysis were stable. The major causes for neonatal death included asphyxia, respiratory distress syndrome, and infection.

Conclusions: The hospitalized neonatal mortality showed a tendency of decrease, which differed based on gender, region, gestational age, and birth weight.

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Figures

Figure 1
Figure 1
Study flowchart.
Figure 2
Figure 2
Forest plot for the neonatal mortality in hospital cases.
Figure 3
Figure 3
Funnel plot with pseudo 95% CI.
See this image and copyright information in PMC

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References

    1. Kochanek K. D., Kirmeyer S. E., Martin J. A., Strobino D. M., Guyer B. Annual summary of vital statistics: 2009. Pediatrics. 2012;129(2):338–348. doi: 10.1542/peds.2011-3435. - DOI - PMC - PubMed
    1. Blencowe H., Cousens S. Review: addressing the challenge of neonatal mortality. Tropical Medicine & International Health. 2013;18(3):303–312. doi: 10.1111/tmi.12048. - DOI - PubMed
    1. Patel R. M., Kandefer S., Walsh M. C., et al. Causes and Timing of Death in Extremely Premature Infants from 2000 through 2011. The New England Journal of Medicine. 2015;372(4):331–340. doi: 10.1056/NEJMoa1403489. - DOI - PMC - PubMed
    1. Liu L., Johnson H., Cousens S. Global, regional and national causes of child mortality: an update systematic analysis for 2010 with time trends since 2000. The Lancet. 2012;379(9832):2151–2161. doi: 10.1016/S0140-6736(12)60560-1. - DOI - PubMed
    1. Oestergaard M. Z., Inoue M., Yoshida S. Neonatal mortality levels for 193 countries in 2009 with trends since 1990: a systematic analysis of progress, projections, and priorities. PLoS Medicine. 2011;8(8) doi: 10.1371/journal.pmed.1001080.e1001080 - DOI - PMC - PubMed

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