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. 2019:1935:79-89.
doi: 10.1007/978-1-4939-9057-3_5.

Rare Cell Type Detection

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Rare Cell Type Detection

Lan Jiang. Methods Mol Biol. 2019.

Abstract

High-throughput single-cell technologies have great potential to discover new cell types. Here, we present a novel computational method, called GiniClust (Jiang et al., Genome Biol 17(1):144, 2016), to overcome the challenge of detecting rare cell types that are distinct from a large population.

Keywords: Clustering; Gini index; RNA-seq; Rare cell type; Single-cell analysis; qPCR.

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