Preparing next-generation scientists for biomedical big data: artificial intelligence approaches
- PMID: 30760118
- PMCID: PMC7545355
- DOI: 10.2217/pme-2018-0145
Preparing next-generation scientists for biomedical big data: artificial intelligence approaches
Abstract
Personalized medicine is being realized by our ability to measure biological and environmental information about patients. Much of these data are being stored in electronic health records yielding big data that presents challenges for its management and analysis. Here, we review several areas of knowledge that are necessary for next-generation scientists to fully realize the potential of biomedical big data. We begin with an overview of big data and its storage and management. We then review statistics and data science as foundational topics followed by a core curriculum of artificial intelligence, machine learning and natural language processing that are needed to develop predictive models for clinical decision making. We end with some specific training recommendations for preparing next-generation scientists for biomedical big data.
Similar articles
-
Big Dreams With Big Data! Use of Clinical Informatics to Inform Biomarker Discovery.Clin Transl Gastroenterol. 2019 Mar;10(3):e00018. doi: 10.14309/ctg.0000000000000018. Clin Transl Gastroenterol. 2019. PMID: 30908310 Free PMC article.
-
Perspective of artificial intelligence in healthcare data management: A journey towards precision medicine.Comput Biol Med. 2023 Aug;162:107051. doi: 10.1016/j.compbiomed.2023.107051. Epub 2023 May 30. Comput Biol Med. 2023. PMID: 37271113 Review.
-
Translating cancer genomics into precision medicine with artificial intelligence: applications, challenges and future perspectives.Hum Genet. 2019 Feb;138(2):109-124. doi: 10.1007/s00439-019-01970-5. Epub 2019 Jan 22. Hum Genet. 2019. PMID: 30671672 Free PMC article. Review.
-
ASAS-NANP symposium: mathematical modeling in animal nutrition-Making sense of big data and machine learning: how open-source code can advance training of animal scientists.J Anim Sci. 2023 Jan 3;101:skad317. doi: 10.1093/jas/skad317. J Anim Sci. 2023. PMID: 37997926 Free PMC article.
-
Big Data Analysis and Machine Learning in Intensive Care Units.Med Intensiva (Engl Ed). 2019 Oct;43(7):416-426. doi: 10.1016/j.medin.2018.10.007. Epub 2018 Dec 24. Med Intensiva (Engl Ed). 2019. PMID: 30591356 Review. English, Spanish.
Cited by
-
Big data analytics and machine learning in hematology: Transformative insights, applications and challenges.Medicine (Baltimore). 2025 Mar 7;104(10):e41766. doi: 10.1097/MD.0000000000041766. Medicine (Baltimore). 2025. PMID: 40068020 Free PMC article. Review.
-
Impact of big data resources on clinicians' activation of prior medical knowledge.Heliyon. 2022 Aug 27;8(9):e10312. doi: 10.1016/j.heliyon.2022.e10312. eCollection 2022 Sep. Heliyon. 2022. PMID: 36105474 Free PMC article.
-
Timing errors and temporal uncertainty in clinical databases-A narrative review.Front Digit Health. 2022 Aug 18;4:932599. doi: 10.3389/fdgth.2022.932599. eCollection 2022. Front Digit Health. 2022. PMID: 36060541 Free PMC article. Review.
-
scGCN is a graph convolutional networks algorithm for knowledge transfer in single cell omics.Nat Commun. 2021 Jun 22;12(1):3826. doi: 10.1038/s41467-021-24172-y. Nat Commun. 2021. PMID: 34158507 Free PMC article.
-
Transcriptomics and epigenetic data integration learning module on Google Cloud.Brief Bioinform. 2024 Jul 23;25(Supplement_1):bbae352. doi: 10.1093/bib/bbae352. Brief Bioinform. 2024. PMID: 39101486 Free PMC article.
References
-
- Council NR. Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease [Internet]. Available from: https://www.nap.edu/catalog/13284/toward-precision-medicine-building-a-k.... - PubMed
-
- Erlewyn-Lajeunesse M, Brathwaite N, Lucas JSA, Warner JO. Recommendations for the administration of influenza vaccine in children allergic to egg. BMJ. 339, b3680 (2009). - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources