Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2019 Feb 13;23(1):46.
doi: 10.1186/s13054-019-2325-9.

Current place of probiotics for VAP

Harjeet Singh Virk  1 , W Joost Wiersinga  2
Affiliations
Editorial

Current place of probiotics for VAP

Harjeet Singh Virk et al. Crit Care. .
No abstract available

Keywords: Gut microbiota; Probiotics; Randomised controlled trial (RCT); Synbiotics; Ventilator-associated pneumonia (VAP).

PubMed Disclaimer

Conflict of interest statement

Ethics approval and consent to participate

Not applicable

Consent for publication

Not applicable

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
The gut-lung axis in ventilator-associated pneumonia (VAP) and proposed working mechanism of probiotics. IL interleukin, TGF-β transforming growth factor-β, SCFA short-chain fatty acids
See this image and copyright information in PMC

Comment on

References

    1. Suez J, Zmora N, Zilberman-Schapira G, et al. Post-antibiotic gut mucosal microbiome reconstitution is impaired by probiotics and improved by autologous FMT. Cell. 2018;174(6):1406–1423. doi: 10.1016/j.cell.2018.08.047. - DOI - PubMed
    1. Lankelma JM, van Vught LA, Belzer C, et al. Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study. Intensive Care Med. 2017;43(1):59–68. doi: 10.1007/s00134-016-4613-z. - DOI - PMC - PubMed
    1. Wischmeyer PE, McDonald D, Knight R. Role of the microbiome, probiotics, and ‘dysbiosis therapy’ in critical illness. Curr Opin Crit Care. 2016;22(4):347–353. doi: 10.1097/MCC.0000000000000321. - DOI - PMC - PubMed
    1. Haak BW, Prescott HC, Wiersinga WJ. Therapeutic potential of the gut microbiota in the prevention and treatment of sepsis. Front Immunol. 2018;9:2042. doi: 10.3389/fimmu.2018.02042. - DOI - PMC - PubMed
    1. Schmidt TSB, Raes J, Bork P. The human gut microbiome: from association to modulation. Cell. 2018;172(6):1198–1215. doi: 10.1016/j.cell.2018.02.044. - DOI - PubMed