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. 2019 Sep;23(9):1936-1939.
doi: 10.1007/s11605-019-04132-0. Epub 2019 Feb 13.

Gastric Plexiform Fibromyxoma

Sudeep Banerjee  1   2 , Jorge de la Torre  1 , Adam M Burgoyne  3 , Ann M Ponsford Tipps  4 , Thomas J Savides  5 , Jason K Sicklick  6
Affiliations

Gastric Plexiform Fibromyxoma

Sudeep Banerjee et al. J Gastrointest Surg. 2019 Sep.
No abstract available

Keywords: Gastric mass; Gastrointestinal stromal tumor; Plexiform angiomyxoid myofibroblastic tumor; Submucosal tumor.

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Conflict of interest statement

Conflict of Interest

J.K.S. has research funding from Novartis Pharmaceuticals, Amgen Pharmaceuticals and Foundation Medicine. J.K.S. also serves or served as Consultant to the following organizations: Grand Rounds (2015–18), and Loxo Oncology (2017–18). These disclosures had no impact on any of the work presented in this manuscript. No other authors have any conflict of interests to declare.

Figures

Figure 1:
Figure 1:
65-year old male with upper gastrointestinal symptoms. (a-b) Abdominal computed tomography with 5.0-cm endophytic gastric mass. (c) Upper endoscopy shows an endophytic mass within gastric antrum with luminal ulceration. (d) Endoscopic ultrasound demonstrates submucosal location of tumor. (e) In situ location of tumor along lesser curvature of gastric antrum. (f) Explanted specimen following resection.
Figure 2:
Figure 2:
Histopathologic analysis consistent with plexiform fibromyxoma. (a) Hemotoxylin and eosin (H&E) staining showing myxoid bland spindle cells and prominent thin capillaries, as well as (b) invasion of the submucosa and muscularis propria. Photomicrographs of (c) α-SMA and (d) c-KIT on immunohistochemical (IHC) staining.
See this image and copyright information in PMC

References

    1. Szurian K et al. Rarity among benign gastric tumors: Plexiform fibromyxoma - Report of two cases. World journal of gastroenterology 23, 5817–5822, doi:10.3748/wjg.v23.i31.5817 (2017). - DOI - PMC - PubMed
    1. Miettinen M, Makhlouf HR, Sobin LH & Lasota J Plexiform Fibromyxoma: A Distinctive Benign Gastric Antral Neoplasm Not to be Confused With a Myxoid Gist. The American journal of surgical pathology 33, 1624–1632, doi:10.1097/PAS.0B013E3181AE666A (2009). - DOI - PubMed
    1. Morris MW, Sullivan L, Sawaya DE, Steiner MA & Nowicki MJ Gastric plexiform fibromyxoma tumor in a child – Case report and review of the literature. Journal of Pediatric Surgery Case Reports Volume 4, Pages 38–41 (2016).

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