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. 2019 Jun:70:9-14.
doi: 10.1016/j.meegid.2019.02.008. Epub 2019 Feb 11.

Plasmodium ovale curtisi and Plasmodium ovale wallikeri in Chinese travelers: Prevalence of novel genotypes of circumsporozoite protein in the African continent

Feng Lu  1 , Md Atique Ahmed  2 , Simin Xu  3 , Sui Xu  4 , Jin-Hee Han  2 , Qianyan Liu  3 , Jing Chen  4 , Guoding Zhu  4 , Huayun Zhou  4 , Jun Cao  5 , Eun-Taek Han  6
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Plasmodium ovale curtisi and Plasmodium ovale wallikeri in Chinese travelers: Prevalence of novel genotypes of circumsporozoite protein in the African continent

Feng Lu et al. Infect Genet Evol. 2019 Jun.

Abstract

Imported malaria due to Plasmodium ovale curtisi and P. ovale wallikeri infections from African countries has increased recently (2011-2014) in Chinese travelers. We report novel genotypes, their prevalence and the predominant haplotypes of P. ovale curtisi and P. ovale wallikeri circumsporozoite protein (CSP) from 20 African countries in Chinese travelers. These genotypes should be considered while designing a CSP-based vaccine against P. ovale malaria.

Keywords: Africa; China; Circumsporozoite protein; Genotypes; Imported case; Plasmodium ovale.

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