Radiochemical isolation method for the production of ^52gMn from ^natCr for accelerator targets

Kendall E Barrett¹, Eduardo Aluicio-Sarduy¹, Aeli P Olson¹, Christopher J Kutyreff¹, Paul A Ellison¹, Todd E Barnhart¹, Robert J Nickles¹, Jonathan W Engle²

Affiliations

¹ University of Wisconsin Department of Medical Physics, 1111 Highland Avenue, Madison, WI, 53711, USA.
² University of Wisconsin Department of Medical Physics, 1111 Highland Avenue, Madison, WI, 53711, USA; University of Wisconsin Department of Radiology, 600 Highland Avenue, Madison, WI, 53792, USA. Electronic address: jwengle@wisc.edu.

PMID: 30763821
DOI: 10.1016/j.apradiso.2019.01.025

Radiochemical isolation method for the production of ^52gMn from ^natCr for accelerator targets

Kendall E Barrett et al. Appl Radiat Isot. 2019 Apr.

. 2019 Apr:146:99-103.

doi: 10.1016/j.apradiso.2019.01.025. Epub 2019 Feb 1.

Authors

Kendall E Barrett¹, Eduardo Aluicio-Sarduy¹, Aeli P Olson¹, Christopher J Kutyreff¹, Paul A Ellison¹, Todd E Barnhart¹, Robert J Nickles¹, Jonathan W Engle²

Affiliations

¹ University of Wisconsin Department of Medical Physics, 1111 Highland Avenue, Madison, WI, 53711, USA.
² University of Wisconsin Department of Medical Physics, 1111 Highland Avenue, Madison, WI, 53711, USA; University of Wisconsin Department of Radiology, 600 Highland Avenue, Madison, WI, 53792, USA. Electronic address: jwengle@wisc.edu.

PMID: 30763821
DOI: 10.1016/j.apradiso.2019.01.025

Abstract

We report a novel, precipitation-based method for the isolation of Mn from Cr targets for cyclotron production of ^52gMn. The separation produces no-carrier-added ^52gMn with a decay corrected radiochemical yield of 85 ± 3% and apparent molar activity for DOTA of 1.3 GBq/μmol. This method reduces stable metallic impurities in the purified ^52gMn compared to previously reported chromatographic methods.

Keywords: (52g)Mn; Cyclotron; DOTA; Precipitation; Radionuclide production.

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Radiochemical isolation method for the production of ^52gMn from ^natCr for accelerator targets

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Radiochemical isolation method for the production of ^52gMn from ^natCr for accelerator targets

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