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Case Reports
. 2020;29(1):90-93.
doi: 10.1159/000498909. Epub 2019 Feb 14.

Whipple's Disease: A Case Report

Orkide Kutlu  1 , Selma Şengiz Erhan  2 , Yasemin Gökden  3 , Özlem Kandemir  3 , Tufan Tükek  4
Affiliations
Case Reports

Whipple's Disease: A Case Report

Orkide Kutlu et al. Med Princ Pract. 2020.

Abstract

Objective: Whipple's disease is a very rare systemic infectious disease with an annual incidence of 3 in one million, which may be fatal if not diagnosed and treated appropriately.

Clinical presentation and intervention: Herein we describe a 49-year-old patient admitted to the hospital with symptoms of severe malabsorption and diagnosed with Whipple's disease. The diagnosis was based on the histopathological findings of small intestine biopsies and PCR analysis.

Conclusion: Whipple's disease should be kept in mind while dealing with patients with severe malabsorption, even in the absence of accompanying features of the disease.

Keywords: Malabsorption; Tropheryma whipplei; Whipple’s disease.

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Conflict of interest statement

Dr. Kutlu has nothing to disclose.

Figures

Fig. 1
Fig. 1
a Foamy macrophages stained for CD68. ×400. b PAS-positive intracytoplasmic eosinophilic granules. ×400. c PAS-D-positive intracytoplasmic eosinophilic granules. ×400.
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