Lung Microbiota Promote Lung Cancer
- PMID: 30765334
- DOI: 10.1158/2159-8290.CD-NB2019-019
Lung Microbiota Promote Lung Cancer
Abstract
In mice predisposed to lung cancer, dysregulation of the lung's bacteria creates a proinflammatory environment that promotes tumor growth. Treating the animals with antibiotics or keeping them in bacteria-free conditions results in fewer and smaller tumors, implicating the local microbiota in the development of lung cancer.
©2019 American Association for Cancer Research.
Comment on
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Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.Cell. 2019 Feb 21;176(5):998-1013.e16. doi: 10.1016/j.cell.2018.12.040. Epub 2019 Jan 31. Cell. 2019. PMID: 30712876 Free PMC article.
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