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. 2015 May;32(Suppl 4):54S-55S.

New Treatments for Chronic Lymphocytic Leukemia

Anita Aggarwal  1
Affiliations

New Treatments for Chronic Lymphocytic Leukemia

Anita Aggarwal. Fed Pract. 2015 May.

Abstract

The treatment of chronic lymphocytic leukemia has undergone a dramatic transformation since the FDA approved new, targeted agents, but patients and doctors must also consider cost and toxicity.

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Conflict of interest statement

Author disclosures The author reports no actual or potential conflicts of interest with regard to this article.

References

    1. Bosch F, Ferrer A, Villamor N, et al. Fludarabine, cyclophosphamide, and mitoxantrone as initial therapy of chronic lymphocytic leukemia: high response rate and disease eradication. Clin Cancer Res. 2008;14(1):155–161. - PubMed
    1. Byrd JC, Gribben JG, Peterson BL, et al. Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. J Clin Oncol. 2006;24(3):437–443. - PubMed
    1. Eichhorst BF, Busch R, Stilgenbauer S, et al. German CLL Study Group (GCLLSG) First-line therapy with fludarabine compared with chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemia. Blood. 2009;114(16):3382–3391. - PubMed
    1. Robak T, Dmoszynska A, Solal-Céligny P, et al. Rituximab plus fludarabine and cyclophosphamide prolongs progression-free survival compared with fludarabine and cyclophosphamide alone in previously treated chronic lymphocytic leukemia. J Clin Oncol. 2010;28(10):1756–1765. - PubMed
    1. Byrd JC, Furman RR, Coutre SE, et al. Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med. 2013;369(1):32–42. - PMC - PubMed

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