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. 2019 Feb 15;20(1):11.
doi: 10.1186/s40360-019-0291-0.

Burden of paraquat poisoning in the department of Antioquia, Colombia

Jefferson Antonio Buendía  1 , Gabriel Jaime Restrepo Chavarriaga  2 , Andrés F Zuluaga  2
Affiliations

Burden of paraquat poisoning in the department of Antioquia, Colombia

Jefferson Antonio Buendía et al. BMC Pharmacol Toxicol. .

Abstract

Background: Paraquat (PQ) poisoning is a public health problem in many regions of Colombia. This study aimed to estimate the burden of PQ poisoning in the Department of Antioquia, Colombia.

Methods: Disability-adjusted life year (DALYs) were calculated as the sum of years of life lost (YLL) and years of life lived with disability (YLD) due to paraquat poisoning in Antioquia; a bootstrapped method with 1000 iterations was used to estimate each statistical parameter using the package DALY calculator in R. For this instance, the annual incidence of paraquat poisoning was obtained from the reported surveillance data according to regional Government.

Results: From 2010 to 2016, 3299 DALYs were estimated in the department of Antioquia for PQ intoxication, with a rate of 53.4 DALYs per 100,000 inhabitants. The majority of the DALYs (2852 DALYs) were generated for men ranging from 15 to 44 years old.

Conclusion: The rate of DALYs reported here is higher than that reported by all chemical poisonings. Better strategies to regulate and restrict the market of this dangerous products are required in Colombia.

Keywords: Colombia; Global burden of disease; Incidence; Mortality; Paraquat; Poisoning.

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Conflict of interest statement

Ethics approval

This study was approved by the Institutional Review Board of University of Antioquia (2015–4690).

Consent for publication

All authors consent this paper for publication.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Sensibility analysis. mrt1.M3: men’s mortality 15–44 years, mrt1.F3: female’s mortality 15–44 years, mrt1.F4: female’s mortality 45–59 years, mrt1.M4: men’s mortality 45–59 years, DWt2: disability weights of PQ acute intoxication
See this image and copyright information in PMC

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